{"id":379,"date":"2017-06-01T15:36:32","date_gmt":"2017-06-01T13:36:32","guid":{"rendered":"http:\/\/ferticent.forma.sk\/?p=379"},"modified":"2025-08-05T12:34:20","modified_gmt":"2025-08-05T10:34:20","slug":"laboratorne-metody","status":"publish","type":"post","link":"https:\/\/ferticent.com\/hu\/laboratorne-metody\/","title":{"rendered":"Laborat\u00f3riumi m\u00f3dszerek"},"content":{"rendered":"<p><\/p>\n<h2>Laborat\u00f3riumi m\u00f3dszerek<\/h2>\n<div class=\"selection-links\">\n<div class=\"selection\"><a href=\"#icsi\">ICSI<\/a>\u00a0<a href=\"#picsi\">PICSI<\/a> <a href=\"#macs\">MACS<\/a> <a href=\"#mesatese\">MESA\/TESE<\/a> <a href=\"#predl_kultivacia\">Blasztocisztateny\u00e9szt\u00e9s<\/a> <a href=\"#maturacia\">Az petesejtek in vitro \u00e9rlel\u00e9se<\/a> <a href=\"#mrazenie\">Az embri\u00f3k fagyaszt\u00e1sa<\/a> <a href=\"#azh\">AZH<\/a> <a href=\"#spf\">SPF<\/a> <a href=\"#glue\">EmbryoGlue<\/a> <a href=\"#vysetr\">Preimplant\u00e1ci\u00f3s genetikai vizsg\u00e1lat<\/a><\/div>\n<\/div>\n<div class=\"selection\">\u00a0<\/div>\n<div class=\"selection\">\n<h3 id=\"icsi\">ICSI- intracytoplasmatic sperm injection<\/h3>\n<p>A h\u00edmivarsejtnek az \u00e9rett petesejtbe val\u00f3 befecskendez\u00e9se mikroszk\u00f3p seg\u00edts\u00e9g\u00e9vel. Ezt a m\u00f3dszert a s\u00falyos f\u00e9rfimedd\u0151s\u00e9g kezel\u00e9s\u00e9n\u00e9l haszn\u00e1ljuk , vagy olyan esetekben ha a klasszikus megterm\u00e9keny\u00fcl\u00e9s nem j\u00e1rt sikerrel. Javasoljuk id\u0151sebb p\u00e1ciensek eset\u00e9ben vagy abban az eseteben ha csak kissz\u00e1m\u00fa petesejt \u00e1ll rendelkez\u00e9sre.<\/p>\n<h3 id=\"picsi\">PICSI- preselected\u00a0intracytoplasmatic sperm injection<\/h3>\n<p>A m\u00f3dszer lehet\u0151v\u00e9 teszi, hogy az\u00a0 ICSI elj\u00e1r\u00e1s seg\u00edts\u00e9g\u00e9vel a megterm\u00e9keny\u00edt\u00e9sre \u00e9rett h\u00edmivarsejtet ker\u00fclj\u00f6n. A spermiumok egy speci\u00e1lis hialuron\u00e1t-tartalm\u00fa g\u00e9lre\u00a0 vannak r\u00e1csepegtetve. A megterm\u00e9keny\u00edt\u00e9shez csak a g\u00e9lhez kapcsol\u00f3d\u00f3 sperm\u00e1kat alkalmazz\u00e1k. Ilyen kapcsol\u00f3d\u00e1sra csak az \u00e9rett spermiumok k\u00e9pesek.<\/p>\n<h3 id=\"macs\">MACS<sup>\u00ae<\/sup> sperm separation- magnetic-activated cell sorting on sperm<\/h3>\n<p>A megterm\u00e9keny\u00edt\u00e9sre alkalmas spermiumoknak a rossz min\u0151s\u00e9g\u0171 spermiumokt\u00f3l (s\u00e9r\u00fclt DNS-el rendelkez\u0151) val\u00f3 elv\u00e1laszt\u00e1sa m\u00e1gneses szepar\u00e1ci\u00f3 seg\u00edts\u00e9g\u00e9vel.<\/p>\n<p>Ezeknek a m\u00f3dszereknek a haszn\u00e1lata megmagyar\u00e1zhatatlan medd\u0151s\u00e9g, ism\u00e9telt sikertelen embri\u00f3implant\u00e1ci\u00f3, az embri\u00f3fejl\u0151d\u00e9s le\u00e1ll\u00e1sa az embri\u00f3be\u00fcltet\u00e9s\u00a0 el\u0151tt \u00e9s nem megfelel\u0151 spermiogram param\u00e9terek eset\u00e9n aj\u00e1nlott.<\/p>\n<h3>\u00a0<\/h3>\n<h3 id=\"mesatese\">MESA, TESE-\u00a0Micro Epididymal Sperm Aspiration\/Testicular Sperm Extraction<\/h3>\n<p>Egy seb\u00e9szeti elj\u00e1r\u00e1sr\u00f3l van sz\u00f3 amely seg\u00edts\u00e9g\u00e9vel megterm\u00e9keny\u00edt\u00e9sre alkalmas h\u00edmivarsejteket nyer\u00fcnk a heresz\u00f6vetb\u0151l vagy a mell\u00e9kher\u00e9kb\u0151l.\u00a0 A beavatkoz\u00e1st a f\u00e9rfimedd\u0151s\u00e9g legs\u00falyosabb eseteiben alkalmazzuk, amikor az ond\u00f3ban nem tal\u00e1lhat\u00f3k megterm\u00e9keny\u00edt\u00e9sre alkalmas spermiumok (azoospermia).<\/p>\n<h3>\u00a0<\/h3>\n<h3 id=\"predl_kultivacia\">Blasztocisztateny\u00e9szt\u00e9s<\/h3>\n<p>Az embri\u00f3knak a megterm\u00e9keny\u00edt\u00e9s ut\u00e1n speci\u00e1lis t\u00e1poldatban val\u00f3 teny\u00e9szt\u00e9se 5-6 napig, am\u00edg el nem \u00e9rik a blasztociszta szakaszt. Lehet\u0151v\u00e9 teszi a leg\u00e9letk\u00e9pesebb embri\u00f3k term\u00e9szetes kiv\u00e1laszt\u00e1s\u00e1t, amelyek a legnagyobb megtapad\u00e1si es\u00e9llyel rendelkeznek. Aj\u00e1nlott ha nagyobb sz\u00e1m\u00fa embri\u00f3 \u00e1ll rendelkez\u00e9sre.<\/p>\n<h3>\u00a0<\/h3>\n<h3 id=\"maturacia\">Az pet\u00e9k in vitro \u00e9rlel\u00e9se<\/h3>\n<p>A petef\u00e9szkekb\u0151l nyert \u00e9retlen pet\u00e9ket tov\u00e1bbi 36-48 \u00f3r\u00e1n \u00e1t tov\u00e1bb \u00e9rlelj\u00fck egy speci\u00e1lis t\u00e1poldatban az inkub\u00e1torban. A be\u00e9rett pet\u00e9k ezut\u00e1n meg vannak term\u00e9keny\u00edtve,\u00a0 a keletkezett\u00a0 embri\u00f3k\u00a0 pedig behelyez\u00e9sre ker\u00fclnek \u00e9pp\u00fagy mint a klasszikus IVF ciklusban.<\/p>\n<h3>\u00a0<\/h3>\n<h3 id=\"mrazenie\">Az embri\u00f3k m\u00e9lyfagyaszt\u00e1sa<\/h3>\n<p>Be\u00fcltet\u00e9sre 1 legfeljebb 2 embri\u00f3 ker\u00fclhet. T\u00f6bb \u00e9letk\u00e9pes embri\u00f3 eset\u00e9n ezek m\u00e9lyfagyaszt\u00e1sa javasolt. A fagyasztva t\u00e1rolt embri\u00f3k be\u00fcltet\u00e9se\u00a0 nem ig\u00e9nyel komolyabb hormon\u00e1lis stimul\u00e1ci\u00f3t.<\/p>\n<h3>\u00a0<\/h3>\n<h3 id=\"azh\">AZH- Assziszt\u00e1lt hatching<\/h3>\n<p>A petresejtet k\u00f6r\u00fclvev\u0151 burok megrepeszt\u00e9se. Az embri\u00f3 csak azut\u00e1n \u00e1gyaz\u00f3dik be a m\u00e9h ny\u00e1lkah\u00e1rty\u00e1j\u00e1ba, miut\u00e1n elhagyta az \u0151t k\u00f6r\u00fclvev\u0151 v\u00e9d\u0151burkot amely az embri\u00f3t v\u00e9di az oszt\u00f3d\u00e1s sor\u00e1n. Esetenk\u00e9nt ez a v\u00e9d\u0151burok megvastagodott ami lehetetlenn\u00e9 teszi az embri\u00f3nak a be\u00e1gyaz\u00f3d\u00e1st . Ebben az esetben az embriol\u00f3gus l\u00e9zersug\u00e1r seg\u00edts\u00e9g\u00e9vel egy olyan ny\u00edl\u00e1st hozz l\u00e9tre, amelyen kereszt\u00fcl az embri\u00f3 kiker\u00fclhet a burokb\u00f3l .<\/p>\n<h3>\u00a0<\/h3>\n<h3 id=\"spf\">SPF (Seminal Plasma Flushing)<\/h3>\n<p>A partner laborat\u00f3riumi k\u00f6r\u00fclm\u00e9nyek k\u00f6z\u00f6tt megmunk\u00e1lt ond\u00f3j\u00e1t a m\u00e9hnyakba fecskendezz\u00fck\u00a0 a pet\u00e9k lesz\u00edv\u00e1sa ut\u00e1n. Ez a m\u00f3dszer serkenti a m\u00e9h ny\u00e1lkah\u00e1rty\u00e1j\u00e1t \u00e9s n\u00f6veli az embri\u00f3 be\u00e1gyaz\u00f3d\u00e1s\u00e1nak es\u00e9ly\u00e9t.<\/p>\n<h3>\u00a0<\/h3>\n<h3 id=\"glue\">EmbryoGlue<\/h3>\n<p>Az EmbryoGlue\u00ae egy speci\u00e1lis embri\u00f3megtapad\u00e1st el\u0151seg\u00edt\u0151 t\u00e1ptalaj amely az embri\u00f3k m\u00e9h\u00fcregbe val\u00f3 visszahelyez\u00e9s\u00e9n\u00e9l alkalmazunk. Ez a\u00a0t\u00e1ptalaj az embri\u00f3k sz\u00e1m\u00e1ra l\u00e9tfontoss\u00e1g\u00fa alkot\u00f3elemeken k\u00edv\u00fcl egy term\u00e9szetesen a\u00a0m\u00e9h\u00fcregben el\u0151fordul\u00f3 polimert \u00fan. hialuron\u00e1tot tartalmaz . A\u00a0hialuron\u00e1t a\u00a0m\u00e9h\u00fcregben az embri\u00f3 m\u00e9hny\u00e1lkah\u00e1rty\u00e1hoz val\u00f3 hozz\u00e1tapad\u00e1s\u00e1n\u00e1l \u00e9s az embri\u00f3\u00a0be\u00e1gyaz\u00f3d\u00e1s\u00e1n\u00e1l j\u00e1tszik fontos szerepet.<\/p>\n<\/div>\n<div class=\"selection\">\n<h3 id=\"vysetr\">Preimplant\u00e1ci\u00f3s genetikai vizsg\u00e1lat<\/h3>\n<p>Az embri\u00f3k genetikai vizsg\u00e1lata a m\u00e9h\u00fcregbe t\u00f6rt\u00e9n\u0151 \u00e1tvitel el\u0151tt.<\/p>\n<p>PGS &#8211; Az embri\u00f3k sz\u0171r\u0151vizsg\u00e1latszer\u0171 genetikai kivizsg\u00e1l\u00e1sa. A r\u00e9gebben haszn\u00e1lt m\u00f3dszer (FISH) csak korl\u00e1tozott sz\u00e1m\u00fa kromosz\u00f3ma (5-8) vizsg\u00e1lat\u00e1t tette lehet\u0151v\u00e9. Olyan genetikai rendelleness\u00e9gek ut\u00e1n kutatunk amelyek ism\u00e9telt vet\u00e9l\u00e9shez \u00e9s velesz\u00fcletett fejl\u0151d\u00e9si hib\u00e1khoz vezethetnek. Az \u00fajabb m\u00f3dszer (aCGH) lehet\u0151v\u00e9 teszi az eg\u00e9sz DNS vizsg\u00e1lat\u00e1t.<\/p>\n<p>Indik\u00e1ci\u00f3k: 37 \u00e9v feletti \u00e9letkor, ism\u00e9telten sikertelen IVF ciklusok, ism\u00e9telt abortusz, s\u00falyos spermiogramrendelleness\u00e9g, kor\u00e1bbi onkol\u00f3giai kezel\u00e9s<\/p>\n<p>PGD \u200b\u200b- Ebben a vizsg\u00e1latban egy adott genetikai rendelleness\u00e9g felkutat\u00e1s\u00e1ra t\u00f6reksz\u00fcnk. Ezt egy olyan medd\u0151 p\u00e1r embri\u00f3inak vizsg\u00e1lat\u00e1ra haszn\u00e1ljuk, amelyben az egyik partner hordoz\u00f3ja a medd\u0151s\u00e9get okoz\u00f3 kromosz\u00f3ma rendelleness\u00e9get.<\/p>\n<p>PGD \u200b\u200bmonog\u00e9n megbeteged\u00e9sek &#8211; C\u00e9lzott embri\u00f3vizsg\u00e1lat egy ismert genetikai betegs\u00e9g ut\u00e1n kutatva.<\/p>\n<p>A\u00a0 laborat\u00f3riumi m\u00f3dszerek alkalmaz\u00e1sa csak egy el\u0151z\u0151leges embriol\u00f3giai vagy orvosi konzult\u00e1ci\u00f3 ut\u00e1n lehets\u00e9ges.<\/p>\n<\/div>\n<p>","protected":false},"excerpt":{"rendered":"<p>Laborat\u00f3riumi m\u00f3dszerek ICSI\u00a0PICSI MACS MESA\/TESE Blasztocisztateny\u00e9szt\u00e9s Az petesejtek in vitro \u00e9rlel\u00e9se Az embri\u00f3k fagyaszt\u00e1sa AZH SPF EmbryoGlue Preimplant\u00e1ci\u00f3s genetikai vizsg\u00e1lat \u00a0 ICSI- intracytoplasmatic sperm injection A h\u00edmivarsejtnek az \u00e9rett petesejtbe val\u00f3 befecskendez\u00e9se mikroszk\u00f3p seg\u00edts\u00e9g\u00e9vel. Ezt a m\u00f3dszert a s\u00falyos f\u00e9rfimedd\u0151s\u00e9g kezel\u00e9s\u00e9n\u00e9l haszn\u00e1ljuk , vagy olyan esetekben ha a klasszikus megterm\u00e9keny\u00fcl\u00e9s nem j\u00e1rt sikerrel. Javasoljuk id\u0151sebb [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[23],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Laborat\u00f3riumi m\u00f3dszerek - Ferticent Bratislava<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ferticent.com\/laboratorne-metody\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"[:sk]Laborat\u00f3rne met\u00f3dy[:de]Labormethoden[:en]Laboratory techniques[:hu]Laborat\u00f3riumi m\u00f3dszerek - Ferticent Bratislava\" \/>\n<meta property=\"og:description\" content=\"Laborat\u00f3riumi m\u00f3dszerek ICSI\u00a0PICSI MACS MESA\/TESE Blasztocisztateny\u00e9szt\u00e9s Az petesejtek in vitro \u00e9rlel\u00e9se Az embri\u00f3k fagyaszt\u00e1sa AZH SPF EmbryoGlue Preimplant\u00e1ci\u00f3s genetikai vizsg\u00e1lat \u00a0 ICSI- intracytoplasmatic sperm injection A h\u00edmivarsejtnek az \u00e9rett petesejtbe val\u00f3 befecskendez\u00e9se mikroszk\u00f3p seg\u00edts\u00e9g\u00e9vel. Ezt a m\u00f3dszert a s\u00falyos f\u00e9rfimedd\u0151s\u00e9g kezel\u00e9s\u00e9n\u00e9l haszn\u00e1ljuk , vagy olyan esetekben ha a klasszikus megterm\u00e9keny\u00fcl\u00e9s nem j\u00e1rt sikerrel. 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